Report highlights

The Gender Industrial Complex

American Principles Project Foundation · 2024

According to its analysis, the sex-reassignment surgery market size was $4.12 billion in 2022.

Key numbers

  1. 1,152

    adverse event reports for Lupron Depot-Ped since 2013.

    Since 2013, there have been 1,152 adverse event reports for Lupron Depot-Ped, which is used to treat early puberty in pediatric patients and off-label to block puberty to start the process of medicalized gender transitioning.

    See it in the reportOriginal PDF, p. 20

  2. 7 of 18

    gender clinics examined by Reuters will begin puberty blockers on the first visit if there are no “red flags.”

    Seven clinics said that, depending on the age of the child, they will begin prescribing puberty blockers based on the first visit if there are no “red flags.”

    See it in the reportOriginal PDF, p. 21

  3. 28 of 39

    parents of minors told Reuters they felt “pressured or rushed to proceed with treatment.”

    Of that number, 28 said they felt “pressured or rushed to proceed with treatment” for their kids.

    See it in the reportOriginal PDF, p. 21

  4. 2×

    prescriptions of puberty blockers for minors doubled between 2017 and 2021 (Komodo Health).

    Despite so many serious concerns, prescriptions for blockers among minors doubled between 2017 and 2021, according to Komodo Health, a company specializing in products for analyzing medical data.

    See it in the reportOriginal PDF, p. 22

  5. ~7×

    the risk of ischemic stroke for people with gender dysphoria who used hormones; nearly 6× heart attack and 5× pulmonary embolism.

    People with gender dysphoria who used hormones were at nearly seven times the risk of ischemic stroke, nearly six times the risk of heart attack, and nearly five times the risk of pulmonary embolism compared to gender dysphoric people who had never used hormone replacements.

    See it in the reportOriginal PDF, p. 23

  6. 53%

    complication rate reported for double flap phalloplasty in one study (Microsurgery).

    One study published in Microsurgery reported complications as high as 53 percent.

    See it in the reportOriginal PDF, p. 24

  7. 121,882

    children ages 6 to 17 diagnosed with gender dysphoria, 2017–2021 (Komodo Health).

    Komodo concluded that at least 121,882 children ages 6 to 17 were diagnosed with gender dysphoria from 2017 through 2021.

    See it in the reportOriginal PDF, p. 26

  8. 17,683

    U.S. children who began puberty blockers or hormones, 2017–2021 (Komodo Health).

    Of that number, 17,683 U.S. children began using puberty blockers or hormones during that period.

    See it in the reportOriginal PDF, p. 26

  9. 42,000+

    children diagnosed with gender dysphoria in 2021 alone, up 70% from 2020.

    Over 42,000 of those children were diagnosed in 2021 alone—an increase of 70 percent from 2020.

    See it in the reportOriginal PDF, p. 26

  10. 1.6M

    adults and youth identify as transgender in the U.S., about 300,000 of them ages 13–17 (Williams Institute, 2022).

    Indeed, the Williams Institute on Sexual Orientation and Gender Identity Law and Public Policy reported in June 2022 that more than 1.6 million adults (ages 18 and older) and youth (ages 13 to 17) identify as transgender in the United States.

    See it in the reportOriginal PDF, p. 27

  11. 776

    mastectomies on Americans ages 13–17 with a prior gender dysphoria diagnosis, 2019–2021 (Komodo).

    At least 776 mastectomies were performed on Americans ages 13 to 17 with a prior gender dysphoria diagnosis from 2019 to 2021, according to Komodo.

    See it in the reportOriginal PDF, p. 28

  12. 26

    states have Medicaid policies that explicitly cover transgender-related health care.

    At present, 26 states have Medicaid policies that explicitly cover transgender-related health care.

    See it in the reportOriginal PDF, p. 28

  13. 276,000

    of the 1.3 million transgender-identifying adults are enrolled in Medicaid (Williams Institute).

    The Williams Institute estimates that approximately 276,000 of the 1.3 million adults who identify as transgender are enrolled in Medicaid.

    See it in the reportOriginal PDF, p. 28

  14. $4.12B

    sex-reassignment surgery market size in 2022 (Grand View Research).

    According to its analysis, the sex-reassignment surgery market size was $4.12 billion in 2022.

    See it in the reportOriginal PDF, p. 31

  15. 8.4%

    expected compound annual growth of the surgery market, 2023–2030.

    That is expected to grow at a compound annual growth rate of 8.4 percent from 2023 to 2030.

    See it in the reportOriginal PDF, p. 31

  16. $205M+

    Cedars-Sinai’s estimated sex-reassignment surgery revenue in 2022, the top provider (Grand View Research).

    At just over $205 million in 2022, Cedars-Sinai Medical Center in Los Angeles was among the top groups for market revenue derived from sex-reassignment surgery.

    See it in the reportOriginal PDF, p. 32

  17. 1 → 2,000+

    patients at Vanderbilt’s transgender clinic in four years.

    Taylor grew the number of patients from just 1 to over 2,000 in four years.

    See it in the reportOriginal PDF, p. 35

  18. $20M+

    in Pennsylvania taxpayer dollars subsidized “gender-affirming care” for minors since 2015 (Pennsylvania Family Institute).

    In October 2023, the Pennsylvania Family Institute reported that over $20 million in state taxpayer dollars had been used to subsidize “gender-affirming care” for minors since 2015.

    See it in the reportOriginal PDF, p. 35

  19. 8,200%+

    increase in Pennsylvania taxpayer funding for these drugs, surgeries and services for children, 2015–2022.

    “From 2015 to 2022, Pennsylvania has had a more than 8,200 percent increase in taxpayer funding for these drugs, surgeries, and services through these state insurance programs for children,” the institute states.

    See it in the reportOriginal PDF, p. 35

  20. $14,000

    per day spent by Pennsylvania in 2022 on transgender services and surgeries.

    According to the institute, the Keystone State was spending almost $14,000 per day in 2022 on transgender services and surgeries.

    See it in the reportOriginal PDF, p. 35

  21. $200B+

    potential size of the gender market: 1.4 million people × a $150,000 minimum cost of transition (RKA, CEO of Euphoria).

    In an interview with Forbes, Robbi Katherine Anthony (who prefers going by RKA), the CEO of transition tech company Euphoria, said the sex-reassignment market could be as big as $200 billion.

    See it in the reportOriginal PDF, p. 37

  22. $37B+

    market implied by 300,000 transgender-identifying 13–17-year-olds at the low-end $124,000 cost of fully transitioning.

    Taking the smaller number and multiplying it by 300,000 still yields a market in excess of $37 billion.

    See it in the reportOriginal PDF, p. 37

In their words

would you rather have a dead daughter or a live son
Chloe Cole’s parents, recalling what they were told, Do No Harm: the ultimatum put to the family of detransitioner Chloe Cole

See it in the reportOriginal PDF, p. 5

My entertaining that lifestyle choice was due to my adverse childhood experiences
Richard Anumene, Do No Harm: The Life of Richard

See it in the reportOriginal PDF, p. 9

The prevention, delay, or whatever pharmacological and especially surgical disruption of the process we call puberty is a crime against humanity
A board-certified plastic surgeon interviewed for the report, Big Business

See it in the reportOriginal PDF, p. 12

The surgeries, the revisions, and all that stuff—it’s big business.
A board-certified plastic surgeon interviewed for the report, Big Business

See it in the reportOriginal PDF, p. 12

And they were not interested in going there because (transgender treatment) was a political hot potato.
Dr. Brad Miller, University of Minnesota Medical School, on drug makers declining to seek FDA approval for gender uses

See it in the reportOriginal PDF, p. 21

a big money maker
Dr. Shayne Taylor, Vanderbilt Clinic for Transgender Health, Known Unknowns, a 2018 lecture

See it in the reportOriginal PDF, p. 34

Introducing that kind of liability to transgender medicine might be the best way to turn the tide
American Principles Project Foundation, Medical Malpractice (conclusion)

See it in the reportOriginal PDF, p. 42

Read the full reportThe original from American Principles Project Foundation